Lung Cancer The Leading Cause Of Cancer Essay - 1555 Words

Lung cancer is the leading cause of cancer-related mortalities in the world. An astounding average of 1.6 million deaths occur due to lung cancer yearly (1). Lung cancer is classified into two types: small cell and non-small cell lung carcinoma (NSCLC), where 85% of lung cancer cases are NSCLC. NSCLC has several different histologic subtypes, some of which are: squamous cell carcinoma, large cell carcinoma, and adenocarcinoma. Of the three, adenocarcinoma accounts for more than 50% of NSCLCs, making it the most common subtype (2). Adenocarcinoma is predominantly present in male smokers, however its occurrence in women, non-smokers, and young patients (below age 40) has been increasing (3). Consequently, genetic alterations / mutations that may be targeted to treat adenocarcinoma are being highly studied, which include: Epidermal Growth Factor Receptor (EGFR), Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK), Thyroid Transcription Factor 1 (TTF1), Napsin A, and more (4). The EGFR mutations are most significantly associated with adenocarcinomas, specifically deletions in Exon 19, and / or point mutations in Exon 21 (5). Similarly, almost 5% of NSCLCs are associated with rearrangements in the ALK gene, resulting in abnormal protein expression that cause highly proliferating cells (6). In the same sense, TTF1 and Napsin A are also genetic alterations frequently associated with adenocarcinomas. Occasionally, the traditional hematoxylin-eosin (HE)-stained slide examinationShow MoreRelatedThe Leading Causes Of Lung Cancer1350 Words   |  6 PagesCenter September 2, 2014 The Leading Causes of Lung Cancer State Standard: 6.4.A Cancer is a disease that plagues millions of people annually (â€Å"Lung†). Lung cancer develops when healthy cells in the lungs are compromised by chemicals, pathogens, or radiation (Henderson). In the early twentieth century, before cigarette smoking and toxic man-made air pollutants became more commonplace, lung cancer was relatively rare (Henderson). It is now the leading cause of cancer deaths worldwide, resulting inRead MoreLung Cancer : The Leading Cause Of Death1286 Words   |  6 PagesLung cancer is one of the leading causes of death not only in the United States of America but globally.1 According to the World Health Organization 8.2 million deaths in 2012 were cancer related and of those deaths, 1.59 million were due specifically to lung cancer.2 In 2014, there was a staggering 224,210 new reported cases of lung cancer in the United States alone. The 5-year relative survival has a 49% to 2% variability depending on the type of lung cancer, stage, and location. T he two majorRead MoreLung Cancer : The Leading Cause Of Death Caused By Cancer1050 Words   |  5 PagesLung cancer has impacted many people’s lives in the world today. Lung cancer is the leading cause of death caused by cancer in the United States (Lewis, 2014, pg. 535). The diagnosis of lung cancer is proceeded by a low cure rate and a high mortality rate. Diagnosis of lung cancer increases the person’s level of physical distress, psychological distress and social isolation (Johnston, 2013). Due to the low cure rate, palliative care becomes essential after the diagnosis of incurable/inoperable lungRead MoreLung Cancer: A Leading Cause of Death Today Essay1593 Words   |  7 PagesLung cancer is on of the leading causes of death today. Lung cancer is a type of neoplasm cancer and is given its name but the site of where the cancer is located. Gale Encyclopedia of Medicine states, â€Å" Most lung cancers develop in the cells that line the bronchi.† Lung cancer can take many years to develop and some have no idea that they even have it until it grows large enough to impede the function of the lungs. There are two different types of tumors the benign, which means that it does notRead MoreLung Cancer : Causes And Effects1329 Words   |  6 PagesThe leading cause of cancer death for both men and women in the United States and worldwide is lung cancer. Lung cancer is responsible for thirty percent of cancer deaths in the United States. The deaths caused by breast cancer, colon cancer and prostate cancer combined do not add up to the deaths that lung cancer causes. In 2007, 158,683 people, 88,243 men and 70,354 women died from lung cancer in the United States (Eldridge, 2012). Out of the 158,683 people that died from lung cancer in 2007, 135Read MoreMorbidity: Lung Cancer1672 Words   |  7 PagesMorbidity-Lung Cancer The human body is designed so that each part is dependent on the other for one or the other reason. There is a delicate balance to the distribution of functions and the way in which each system defenses itself against any unmentionable disease or ailment. However, there are stages in the lives of all humans when the body finds itself in a position where it is no longer able to defend itself against ailments and diseases and eventually may even lose the battle. One suchRead MoreCause And Effect Of Lung Cancer985 Words   |  4 PagesIntroduction The second leading cause of death in the United States as of 1933 is cancer .During this period advancements took place in treatment of infectious diseases such as pneumonia and influenza. Cancer, in turn, took its place and is a chronic illness that has no known cure. There are many different types of cancer that affects different parts of the body but lung cancer is the leading cancer killer in the United States . Cancer of the lungs also known as pulmonary carcinoma is caused by aRead More lung cancer Essay1459 Words   |  6 Pagesnbsp;nbsp;nbsp;nbsp;nbsp;Lung cancer is the most common cancer-related cause of death among men and women. Lung cancer can be undetected for many years causing it to become more dangerous and possibly fatal. There is not cure for lung cancer or any cancer, but if detected in an early stage the lung cancer can be detected, treated, and hopefully terminated. There are many new and developing treatments being tested now that may save lives in the future. Through understanding what the lung cancer is, doctors canRead MoreEssay about Lung Cancer1455 Words   |  6 PagesCancer of the lung was nearly nonexistent in the early 1900’s. By the middle of the 20th century an epidemic became apparent throughout the United States and the rest of the world. It is primarily correlated with the widespread abundance of cigarette smoking in the world. The tobacco industry has multiplied its production immediately prior to World War I. There was a typical 20 to 30 year lagging period between the initiation of cigarette smoking and the actual tumor formation in the lungs. LungRead MoreCancer1029 Words   |  5 PagesLUNG CANCER NAME: INSTRUCTOR: COURSE: DATE: OUTLINE Cancer is a disease that results to an abnormal growth of the cells and form tumors which may spread throughout the body leading to the body malfunction (Radon amp; Raymond, P4). While there are various types of cancer such as lung cancer, prostate cancer, breast cancer among others, this paper will focus on lung cancer and will major in the following: †¢ The main causes of lung cancer †¢ The